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UCLA Oralytics

Published in academic literature

For:General Public & Enthusiasts

App Summary

UCLA Oralytics is an mHealth intervention app designed for individuals at risk of dental disease that delivers personalized prompts to encourage consistent tooth brushing. The associated research describes the design of an online reinforcement learning algorithm used to optimize the timing of these intervention prompts. The authors deployed this system in a clinical trial to evaluate its potential for improving adherence to oral self-care behaviors.

App Screenshots

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Detailed Description

Functionality & Mechanism

Developed at UCLA, Oralytics is a mobile health intervention system engineered to promote adherence to oral self-care behaviors. The system leverages an online reinforcement learning (RL) algorithm to determine optimal times for delivering personalized intervention prompts. This mechanism aims to improve engagement and consistency with recommended tooth brushing habits by personalizing the timing of behavioral cues. The intervention is designed to complement clinician-delivered preventative care for individuals at risk for dental disease.

Evidence & Research Context

  • The system's reinforcement learning algorithm was developed and refined using prior data, domain expertise, and extensive experiments within a simulation test bed, as detailed in its design papers.
  • A re-sampling analysis was conducted to validate key design decisions of the reinforcement learning algorithm for deployment in a clinical trial setting.
  • The Oralytics intervention system and its associated algorithm have been deployed in a registered clinical trial focusing on oral health for at-risk populations.
  • Associated research protocols outline a planned second-phase randomized controlled trial to formally evaluate the system's efficacy in improving health outcomes.

Intended Use & Scope

Oralytics is designed for use by individuals, particularly those at risk for dental disease, as an adjunct to professional preventative care. Its primary utility is to reinforce and support adherence to oral self-care behaviors between clinical visits. The system does not provide clinical diagnoses or treatment recommendations and is not a substitute for professional dental consultation.

Studies & Publications

2 publications

Peer-reviewed research associated with this app.

Development/Design Paper

A Deployed Online Reinforcement Learning Algorithm in an Oral Health Clinical Trial

Trella et al. (2024) · arXiv

Describes the research-driven development of this app
Dental disease is a prevalent chronic condition associated with substantial financial burden, personal suffering, and increased risk of systemic diseases. Despite widespread recommendations for twice-daily tooth brushing, adherence to recommended oral self-care behaviors remains sub-optimal due to factors such as forgetfulness and disengagement. To address this, we developed Oralytics, a mHealth intervention system designed to complement clinician-delivered preventative care for marginalized individuals at risk for dental disease. Oralytics incorporates an online reinforcement learning algorithm to determine optimal times to deliver intervention prompts that encourage oral self-care behaviors. We have deployed Oralytics in a registered clinical trial. The deployment required careful design to manage challenges specific to the clinical trials setting in the U.S. In this paper, we (1) highlight key design decisions of the RL algorithm that address these challenges and (2) conduct a re-sampling analysis to evaluate algorithm design decisions. A second phase (randomized control trial) of Oralytics is planned to start in spring 2025.
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Development/Design Paper

Oralytics Reinforcement Learning Algorithm

Trella et al. (2024) · arXiv

Describes the research-driven development of this app
Dental disease is still one of the most common chronic diseases in the United States. While dental disease is preventable through healthy oral self-care behaviors (OSCB), this basic behavior is not consistently practiced. We have developed Oralytics, an online, reinforcement learning (RL) algorithm that optimizes the delivery of personalized intervention prompts to improve OSCB. In this paper, we offer a full overview of algorithm design decisions made using prior data, domain expertise, and experiments in a simulation test bed. The finalized RL algorithm was deployed in the Oralytics clinical trial, conducted from fall 2023 to summer 2024.
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UCLA Oralytics

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