UCSF WYZ icon

UCSF WYZ

Shows promise in preliminary research

For:Patients & CaregiversKids & Youth

App Summary

UCSF WYZ is a mobile app designed for youth and young adults living with HIV to support their engagement in care and medication adherence through reminders, lab tracking, resource finders, and a peer community. Based on the information-motivation-behavioral skills framework, a preliminary pilot study (N=79) found the app demonstrated high feasibility and acceptability among its intended users. The authors conclude that further research is warranted to examine the app's efficacy for improving engagement in HIV care and antiretroviral therapy adherence.

App Screenshots

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Detailed Description

Functionality & Mechanism

Developed by researchers at the University of California, San Francisco (UCSF), WYZ is a mobile health intervention grounded in the information, motivation, and behavioral skills framework. The system integrates three core modules: 'My Health' facilitates medication and lab result tracking; 'My Team' provides a curated directory of community-based health, housing, and social services; and 'My Community' delivers a secure platform for peer-to-peer communication, medical news, and appointment reminders. The interface was co-designed with a youth advisory board.

Evidence & Research Context

  • A preliminary, single-arm pilot study (N=79) evaluated the app's feasibility and acceptability over six months among youth and young adults living with HIV.
  • The intervention demonstrated high feasibility, meeting or exceeding predefined benchmarks for recruitment (94%), mean weekly logins (5.3), and weekly peer chat engagement (4.8 posts).
  • User-reported acceptability was high, with over 91% of participants favorably rating the app's ease of use, security, and privacy protocols.
  • While the study established feasibility, the authors note that further research is required to determine the app's efficacy for improving engagement in care and ART adherence.

Intended Use & Scope

This app is intended for use by youth and young adults living with HIV as an adjunctive tool to support care engagement and self-management. The platform is designed to enhance medication adherence self-efficacy and facilitate access to community resources. It does not provide medical advice and is not a substitute for professional clinical care.

Studies & Publications

2 publications

Peer-reviewed research associated with this app.

Pilot/Feasibility Study

A Mobile Health App (WYZ) for Engagement in Care and Antiretroviral Therapy Adherence Among Youth and Young Adults Living With HIV: Single-Arm Pilot Intervention Study

Saberi et al. (2020) · JMIR Formative Research

Feasibility confirmed — high user satisfaction and engagement among youth and young adults living with HIV.

Background Youth are globally recognized as being vulnerable to HIV. Younger age has been correlated with worse health outcomes. Mobile health (mHealth) interventions have the potential to interact with youth where they are, using a device they already access. Objective Using predefined benchmarks, we sought to evaluate the feasibility and acceptability of WYZ, an mHealth app, for improved engagement in care and antiretroviral therapy (ART)
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Study Protocol

WYZ: a pilot study protocol for designing and developing a mobile health application for engagement in HIV care and medication adherence in youth and young adults living with HIV

Erguera et al. (2019) · BMJ Open

Research study planned or in progress; results not yet available
Introduction Youth and young adults bear a disproportionate share of the HIV burden and there is a critical need for interventions to curb health disparities experienced among these age groups. The purpose of our research is to build on our theory-guided model and formative research to develop a mobile health application, called WYZ, for improved engagement in HIV care and antiretroviral therapy adherence, and pilot test it among youth and young
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UCSF WYZ

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